Caspases in apoptosis and beyond

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Role of caspases in apoptosis and disease.

Apoptosis, a genetically governed process of eliminating cells in response to a variety of stimuli provides protection against cancer and viral infections as well as maintains homeostasis. Recent studies using both molecular and cloning approaches, and in vitro systems have identified a class of highly specific proteases, termed caspases, that appear to have an important role in apoptotic execu...

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Caspases: the executioners of apoptosis.

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ژورنال

عنوان ژورنال: Oncogene

سال: 2008

ISSN: 0950-9232,1476-5594

DOI: 10.1038/onc.2008.297